Mark Hampton is a professor at the Department of Pathology and Biomedical Science on the University of Otago, Christchurch campus, and director of the Centre for Free Radical Research. Mark completed his undergraduate and PhD studies in New Zealand before taking up postdoctoral positions at the Karolinksa Institute in Sweden and Harvard in the USA. He subsequently returned to the University of Otago where he was promoted to a professorial role in 2013.
Mark focuses on the signalling pathways in cells that are modulated by oxidative stress. His PhD investigated the role that neutrophil oxidants play in killing phagocytosed microbes. His interests then broadened to the impact of these oxidants on neighbouring cells during inflammation, and the controlled generation of oxidants by other cells during normal metabolism.
His current projects include investigations of the ability of oxidants generated by the innate immune system to regulate epigenetic and cell death pathways; how the disruption of redox homeostasis can promote the killing of cancer cells and pathogenic microbes; and how oxidative stress is associated with the biological processes underlying human ageing.